Health Issue: About Breast Cancer
Thursday, July 15, 2010
| Breast cancer: Therapy slows tumour growth London: Scientists have developed a new therapy which they claim could significantly slow tumour growth in patients with advanced breast cancer. An international study has found that the therapy, designed to attack tumours in patients with a genetic mutation in either BRCA1 or BRCA2, slowed tumour growth in 85% of advanced breast cancer patients, :ancet journal reported. The new agent,olaparth, inhibits a protein called PARP Both PARP and the BRCA proteins are involved in DNA repair. And while cells seem to be able to do without one or the other, inhibiting PARP in a tumour that lacks a BRCA gene causes them to die. "If you put too much stress on the cancer cell, it can'tlake it and it falls apart." said lead author Susan Domehek of University of Pennsylvania. |

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